Oooooooew booooy! I'd have to start with the size of the hull, what you expect from it, and what your budget is. It would be fun to spend YOUR money! Har Har!
If you were to stay with an early casting, you may be able to use your existing intake system. Keep in mind that some of the lighter castings are not suitable for marine use.
(see Dennis Moore's "SBC Marine Performance" for some great info)
If you were to go with the Vortec heads, your intake manifold now changes.
In any event, you MUST select pistons and cylinder heads simultaneously, since each selection affects the other!
A good Q/E piston for an early 76cc cylinder head will not work with the 64cc Vortec cylinder head.... for example!
The end result C/R, and the Q area of the piston will be different for these two cylinder heads.
I rarely recommend a camshaft for anyone!
For this, you're better off to speak with an expert at one of the many companies that specialize in this. That is what I would be doing!
Comp Cams, for example.
Make sure that they understand that this is a Marine application, and that you intend to build a 383 version.
This person may also want to know which pistons/heads you are considering!
You may also want to consider a later block, and go with roller cam followers.
Lots of decisions ahead of you!