I'd be more inclined to let engine hours determine when the filter requires replacement, but changing more frequently is certainly not a bad idea.
You may also want to consider how long the fuel has been unused.
As for pre-filling the cartridge......., you can make the call here.
With mechanical fuel pumps, I recommend that we fire the engine up for a short duration, prior to a filter change. (run it long enough to fill the carburetor float bowl)
This is so that the fuel system allows the engine to fire, and in turn, self prime the filter cartridge.
If we do not pre-fill, and if we have an engine that won't fire off quickly, we end cranking needlessly.
With an electric fuel pump, we can circumvent the Start-by-pass circuit, and prime the cartridge with the fuel pump without operating the engine........ In which case the pre-fill is not necessary.
I prefer to pre-fill to about 80%.
An air lock in a carbureted fuel system should be a non-issue. The fuel pump will pull the needed fuel into and through the filter cartridge (priming it), and the carburetor needle/seat should not cause an issue re; any air lock.
MPI and/or FI may be a different story.
BTW, if you want a more true water separating fuel filter system, look at what Parker/RACOR has to offer.
These can be purchased as a retro-fit system to your existing filter base.
Now also sold under the names; GLM, Sierra and Mallory.
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