Ethanol actually keeps your whole fuel system cleaner than (regular) gas.
Yes, it can cause problems for old rubber fuel lines, but generally anything produced from the mid 1970's onward is ok. If you have any concerns a couple feet of bulk hose from any automotive place is a cheap fix.
Ethanol however, is not without it's issues.
It attracts moisture and then over time phase separates so you end up with a watery mess at the bottom of your fuel tank (or in carb bowls if they sit idle long enough).
To combat this the best advice is to ALWAYS run fresh, stablized gas and install an inline water separating filter if you are running any motor larger than a portable.
Why stablize if running fresh all the time? Unless you completely drain your entire fuel system (which can actually be a bad thing), the stablizer will stop the ethanol from phase separating in the system.
Despite your best preventative efforts, you may still end up with fuel system clogs when you initially change over to ethanol enhanced gas.
That's because the ethanol will break down all the varnish, gum and other "cooties" that are stuck in your fuel system (that up until now have sat there silently).
Most "blended" fuels are "no more than 10%" ethanol. I have been running E15 (15%) in four of my outboards (three are mid-80's models, with the "new" one a 91 model) for two seasons now with "zero" adverse affects.
I run portable gas tanks and at the end of the day, the left over gas (even if it's mixed 50:1) goes in my pick-up truck - it doesn't seem to mind when a couple gallons of 50:1 goes into it's 30 gallon gas tank.
If you can't drain your gas tanks then definely run stablizer (rated for ethanol gas), keep the vents tightly closed (to keep moisture out) and for prolonged periods of storage, fill the tanks completely. Less air means less moisture....