This is one of those big debate topics. I used straight weight 30 or 40 in any brand I could find of national recognition and changed the oils 30 to 40 hours. I have been using Mobil 1 synthetic in my 2001 F-150 since about 20,000 mi and today, it has 234,000. It truly runs NO DIFFERENTLY than the day I picked it up. I use it mostly for highway trips and am tickled pink every mile I run.
I discovered, although not cheap, Royal Purple Synthetic Oil is available in straight weight formulas. I am using it this season and although we have about 700 hours on these engines, my top end rebuilds and overall view of the engines show them to be in very good condition. I guess we'll see. From everything I have read since 2009, synthetic oils are superior in all areas of lubrication...again...FROM WHAT I HAVE READ.
In my mind, oil is like the blood in the engine, blah, blah, blah my 2 cents